Analytical Scientist
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Apply Now Application ends in 27d 18h 19min
Job Detail
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Offered Salary 0
Job Description
Responsibilities
·    Act as a subject matter expert in method development, product characterization, formulation development for monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs).
·    Perform analytical testing using techniques such as HPLC (Protein A, SEC, RP, IEC, and HIC), CE-SDS, glycan, peptide mapping, and intact mass LC-MS.
- Design and execute formulation development studies with DLS, SLS, nanoDSF, and MFI to assess thermal, conformational, and solution stabilities as needed.
- Collaborate with cell line, upstream, and downstream development teams to support process development.
·    Lead or support method transfer, qualification, and testing at CDMOs.
·    Conduct compatibility studies of clinical administration components in partnership with analytical and clinical teams.
- Draft and review SOPs, technical reports, and regulatory submission documents, addressing related technical inquiries.
·    Participate in lab management, including reagent and other consumables procurement and equipment maintenance and troubleshooting for equipment failure.
·    Engage in scientific discussions, present findings, and ensure alignment with project timelines.
Qualifications
·    BS in Biochemistry, Chemistry, Chemical Engineering or related field with 0 – 5 years of biotech industry experience or PhD with 0–3 years of relevant experience.
·    Hands-on expertise in analytical methods such as HPLC (SEC, RP, IEC, HIC, Protein A), CE-SDS, and cIEF for mAbs and/or ADCs.
·    Experience with formulation development, Design of Experiments (DOE), and statistical analysis for mAbs and/or ADCs is a plus.
·    Familiarity with DLS, SLS, nanoDSF, MFI, peptide mapping, intact mass LC-MS, and glycan profiling for mAbs and/or ADCs is preferred.
·    Ability to introduce and establish new technologies is advantageous.
·    Strong verbal and written communication skills, attention to detail, and multitasking abilities.
·    Self-motivated, eager to develop new skills, and comfortable working in a fast-moving, small-company environment.
Apply Now
Application ends in 27d 18h 19min