Scientist I/II
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Job Detail
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Offered Salary 0
Job Description
Summary of Position
This position is part of the Protein Science group within the Research department. The Scientist I/II will be responsible for the analysis of biomolecular interactions using Surface Plasmon Resonance (SPR) and Biolayer Interferometry (BLI) to analyze biomolecular interactions, primarily focusing on antibody-antigen binding kinetics in support of the biologics research pipeline. Additional roles include the purification of recombinant proteins and their characterization by HPLC and capillary electrophoresis.
Responsibilities and Job Duties
- Design, execute, and analyze SPR and BLI experiments to determine antibody affinities, kinetics, and epitopes.
- Maintain SPR and BLI instruments
- Purify proteins and perform routine analytical characterization
- Confirm protein identity by Liquid Chromatography-Mass Spectrometry (LC-MS)
- Conduct protein stability tests for lead molecule selection
- Maintain timely and accurate records
Minimum Qualifications
Scientist I
Education & Other Credentials
- Bachelor’s (BS/BA) in Biochemistry or a related scientific field of study with 3+ years of bench-related experience within industry and/or academia.
OR
- A Master’s degree in Biochemistry or a related scientific field of study with 0 years of bench-related experience within industry and/or academia.
Scientist II
Education & Other Credentials
- Bachelor’s (BS/BA) in Biochemistry or a related scientific field of study with 5+ years of strong bench-related experience within industry and/or academia.
OR
- A Master’s degree in Biochemistry or a related scientific field of study with 2+ years of strong bench-related experience within industry and/or academia.
Knowledge, Skills and Abilities
- Understanding of biophysical principles governing protein-protein interactions and binding kinetics
- Hands-on experience with SPR and BLI instruments
- Ability to handle multiple tasks and willing to collaborate with other teams
- Excellent written and verbal communications skills
- Maintain timely and accurate recordsÂ
Preferred Knowledge and Skills
- Knowledge and experience about protein purification
- Hand-on experience with AKTA chromatography system preferred
- Hand-on experience with HPLC or LC-MS preferred